RiboTempo web server

by Gong Zhang

Welcome to our RiboTempo web server.
This web-based program predicts the translation rate profile in E. coli and B. subtilis. The algorithm incorporates calculation of the rate of translation of each codon based on the tRNA concentration and codon selectivity of the cognate tRNA. The algorithm and applications of this program are described in detail in the following papers:
        Transient ribosomal attenuation coordinates protein synthesis and co-translational folding
            Zhang G, Hubalewska M, Ignatova Z
            Nature Structural and Molecular Biology, 2009 Mar;16(3):274-80.
        Generic algorithm to predict the speed of translational elongation: implications for protein biogenesis
            Zhang G, Ignatova Z
            PLoS ONE, 2009;4(4):e5036.

Step 1: Choose an organism:

Step 2: Type/paste your query DNA sequence.
Note: non-letter characters will be automatically deleted. Sequence is case insensitive.

Step 3: Click the button "Calculate" to generate the translation rate profile.
Note: The generated profile is presented in a PNG picture format which can be saved on your local disk. To submit another query, press the "back" button in your browser.

Click here to visit our group homepages:
> Biochemistry, Biochemie und Molekularbiologie, Universität Hamburg, Hamburg, Germany
> Translatomics Lab, Institute of Life and Health Engineering, Jinan University, Guangzhou, China